|Application ||WB, E|
|Other Accession||Q62181, A7MB70|
|Calculated MW||85207 Da|
|Antigen Region||592-620 aa|
|Other Names||Semaphorin-3C, Semaphorin-E, Sema E, SEMA3C, SEMAE|
|Target/Specificity||This SEMA3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 592-620 amino acids from the C-terminal region of human SEMA3C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SEMA3C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).|
|Tissue Location||Expressed intensely in the heart, skeletal muscle, colon, small intestine, ovary, testis, and prostate. Faint expression ubiquitously among other organs, including brain|
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Provided below are standard protocols that you may find useful for product applications.
SEMA3C may be involved in diverse cell survival mechanisms.
Esselens, C., et al. J. Biol. Chem. 285(4):2463-2473(2010)
Kodo, K., et al. Proc. Natl. Acad. Sci. U.S.A. 106(33):13933-13938(2009)
Johnson, A.D., et al. Hum. Mol. Genet. 18(14):2700-2710(2009)
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