|Calculated MW||69,54,34 KDa|
|Antigen Region||445-474 aa|
|Other Names||IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ, IQCB1, KIAA0036, NPHP5|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Involved in ciliogenesis.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Localization to the centrosome depends on the interaction with CEP290|
|Tissue Location||Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors.|
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Provided below are standard protocols that you may find useful for product applications.
Involved in ciliogenesis (By similarity).
Luo X.,et al.Cancer Res. 65:10725-10733(2005).
Otto E.A.,et al.Nat. Genet. 37:282-288(2005).
Nomura N.,et al.DNA Res. 1:27-35(1994).
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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