TEKT4 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q8WW24 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 50649 Da |
Antigen Region | 132-161 aa |
Gene ID | 150483 |
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Other Names | Tektin-4, TEKT4 |
Target/Specificity | This TEKT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human TEKT4. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TEKT4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TEKT4 (HGNC:31012) |
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Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme (PubMed:36191189). Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). Contributes to normal sperm motility (By similarity). |
Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q149S1}. Note=Found in the abaxial (convex) surface of outer dense fibers in sperm flagella {ECO:0000250|UniProtKB:Q149S1} |
Tissue Location | Strongly expressed in spermatozoa. Also detected at low levels in pancreas. Expressed in airway epithelial cells (PubMed:36191189). |
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Provided below are standard protocols that you may find useful for product applications.
Background
TEKT4 is structural component of ciliary and flagellar microtubules. TEKT4 forms filamentous polymers in the walls of ciliary and flagellar microtubules.
References
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
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