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ES8L1 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ES8L1 Antibody AP50836
    Western blot analysis of lysate from human breast tissue lysate,using ES8L1 Antibody, was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
    detail
  • IHC - ES8L1 Antibody AP50836
    Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ES8L1 antibody.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q8TE68
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 82,66,62,56 KDa
Antigen Region 422-450 aa
Additional Information
Gene ID 54869
Other Names Epidermal growth factor receptor kinase substrate 8-like protein 1, EPS8-like protein 1, Epidermal growth factor receptor pathway substrate 8-related protein 1, EPS8-related protein 1, EPS8L1, DRC3, EPS8R1
Dilution WB~~ 1:1000
IHC~~1:50~100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.09% (W/V) sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name EPS8L1
Synonyms DRC3, EPS8R1
Function Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.
Cellular Location Cytoplasm.
Tissue Location Detected in placenta.
Research Areas
Citations (0)
citation

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Background

Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

References

Wu K.,et al.Zhonghua Yi Xue Yi Chuan Xue Za Zhi 16:325-327(1999).
Tocchetti A.,et al.Genomics 81:234-244(2003).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).

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$ 350.00
Cat# AP50836
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Availability: 2 weeks
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