Myelin PLP Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P60201 |
Reactivity | Human, Mouse, Rat, Dog, Rabbit |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 30; [uniprot]30,26; KDa |
Antigen Region | 21-120/277 aa |
Gene ID | 5354 |
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Other Names | Myelin proteolipid protein, PLP, Lipophilin, PLP1, PLP |
Dilution | WB~~ 1:500 IHC-P~~1:100~1:500 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | PLP1 |
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Synonyms | PLP |
Function | This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin. |
Cellular Location | Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
References
Diehl H.-J.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:9807-9811(1986).
Simons R.,et al.Biochem. Biophys. Res. Commun. 146:666-671(1987).
Hudson L.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:8128-8131(1989).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
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