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Myelin PLP Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Myelin PLP Antibody AP50859
    Western blot analysis of lysate from human brain tissue lysate,using Myelin PLP Antibody(AP50859). AP50859 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.
    detail
  • IHC-P - Myelin PLP Antibody AP50859
    Formalin-fixed and paraffin embedded rat brain labeled with Anti-Myelin PLP Polyclonal Antibody, Unconjugated (AP50859) at 1:200 followed by conjugation to the secondary antibody and DAB staining
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P60201
Reactivity Human, Mouse, Rat, Dog, Rabbit
Host Rabbit
Clonality Polyclonal
Calculated MW 30; [uniprot]30,26; KDa
Antigen Region 21-120/277 aa
Additional Information
Gene ID 5354
Other Names Myelin proteolipid protein, PLP, Lipophilin, PLP1, PLP
Dilution WB~~ 1:500
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name PLP1
Synonyms PLP
Function This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.
Cellular Location Cell membrane; Multi-pass membrane protein. Myelin membrane. Note=Colocalizes with SIRT2 in internodal regions, at paranodal axoglial junction and Schmidt-Lanterman incisures of myelin sheat.
Research Areas
Citations (0)
citation

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Background

This is the major myelin protein from the central nervous system. It plays an important role in the formation or maintenance of the multilamellar structure of myelin.

References

Diehl H.-J.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:9807-9811(1986).
Simons R.,et al.Biochem. Biophys. Res. Commun. 146:666-671(1987).
Hudson L.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:8128-8131(1989).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).

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Discontinued
Cat# AP50859
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