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KLF2 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9Y5W3 |
| Reactivity | Human, Mouse, Rat, Rabbit, Sheep |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39;[uniprot]37.4 KDa |
| Antigen Region | 251-355/355 aa |
| Gene ID | 10365 |
|---|---|
| Other Names | Krueppel-like factor 2, Lung krueppel-like factor, KLF2, LKLF |
| Dilution | WB~~ 1:500 IHC~~1:100-1:500 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | KLF2 |
|---|---|
| Synonyms | LKLF |
| Function | Transcription factor that binds to the CACCC box in the promoter of target genes such as HBB/beta globin or NOV and activates their transcription (PubMed:21063504). Might be involved in transcriptional regulation by modulating the binding of the RARA nuclear receptor to RARE DNA elements (PubMed:28167758). |
| Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds to the CACCC box in the beta-globin gene promoter and activates transcription (By similarity).
References
Kozyrev S.V.,et al.FEBS Lett. 448:149-152(1999).
Wani M.A.,et al.Genomics 60:78-86(1999).
Lee H.J.,et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases.
Conkright M.D.,et al.J. Biol. Chem. 276:29299-29306(2001).
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