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GRO Alpha antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - GRO Alpha antibody AP50881
    Western blot analysis of lysate from A375 cell line, using GRO Alpha antibody(AP50881). AP50881 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysate at 20ug.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P09341
Reactivity Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 11.7kD; [uniprot,origene]11;
Additional Information
Gene ID 2919
Other Names Growth-regulated alpha protein, C-X-C motif chemokine 1, GRO-alpha(1-73), Melanoma growth stimulatory activity, MGSA, Neutrophil-activating protein 3, NAP-3, GRO-alpha(4-73), GRO-alpha(5-73), GRO-alpha(6-73), CXCL1, GRO, GRO1, GROA, MGSA, SCYB1
Dilution WB~~ 1:1000
Format0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name CXCL1
Synonyms GRO, GRO1, GROA, MGSA, SCYB1
Function Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO- alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO- alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity.

References

Anisowicz A.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:7188-7192(1987).
Richmond A.,et al.EMBO J. 7:2025-2033(1988).
Baker N.E.,et al.Nucleic Acids Res. 18:6453-6453(1990).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Wuyts A.,et al.Eur. J. Biochem. 260:421-429(1999).

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Discontinued
Cat# AP50881
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