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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Rabbit Anti-IFNGR2 antibody    

Rabbit Anti-IFNGR2 antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • IHC-P - Rabbit Anti-IFNGR2 antibody   AP50884
    Formalin-fixed and paraffin embedded human labeled with Anti-IFNGR2 Polyclonal Antibody, Unconjugated (AP50884) at 1:200 followed by conjugation to the secondary antibody and DAB staining
  • WB - Rabbit Anti-IFNGR2 antibody   AP50884
    Western blot analysis of lysate from A431 cell line, using Rabbit Anti-IFNGR2 antibody (AP50884). AP50884 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody.Lysate at 20ug.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P38484
Reactivity Rat, Dog, Cow
Host Rabbit
Clonality Polyclonal
Calculated MW H=38; KDa
Additional Information
Gene ID 3460
Other Names Interferon gamma receptor 2, IFN-gamma receptor 2, IFN-gamma-R2, Interferon gamma receptor accessory factor 1, AF-1, Interferon gamma transducer 1, IFNGR2, IFNGT1
Dilution IHC-P~~1:100~1:500
WB~~ 1:1000
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name IFNGR2 (HGNC:5440)
Function Associates with IFNGR1 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:8124716, PubMed:7673114,PubMed:7615558). Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:8124716, PubMed:7673114, PubMed:15356148). Required for signal transduction in contrast to other receptor subunit responsible for ligand binding (PubMed:7673114).
Cellular Location Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasm. Note=Has low cell surface expression and high cytoplasmic expression in T cells. The bias towards cytoplasmic expression may be due to ligand-independent receptor internalization and recycling
Tissue Location Expressed in T-cells (at protein level).
Research Areas
Citations (0)

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Background

Part of the receptor for interferon gamma. Required for signal transduction. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2.

References

Soh J.,et al.Cell 76:793-802(1994).
Rhee S.,et al.J. Biol. Chem. 271:28947-28952(1996).
Vogt G.,et al.Nat. Genet. 37:692-700(2005).

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$ 295.00
Cat# AP50884
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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