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>   home   >   Products   >   Primary Antibodies   >   ZACN Antibody (C-term)   

ZACN Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZACN Antibody (C-term) AP5090b
    Western blot analysis of ZACN Antibody (C-term) (Cat. #AP5090b) in A375 cell line lysates (35ug/lane).ZACN (arrow) was detected using the purified Pab.
  • IHC-P - ZACN Antibody (C-term) AP5090b
    ZACN Antibody (C-term) (Cat. #AP5090b) IHC analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ZACN Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q401N2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 45816 Da
Antigen Region 331-360 aa
Additional Information
Gene ID 353174
Other Names Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2, ZACN, L2, LGICZ, LGICZ1, ZAC
Target/Specificity This ZACN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human ZACN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZACN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms L2, LGICZ, LGICZ1, ZAC
Function Zinc-activated ligand-gated ion channel.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus.
Citations (0)

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ZACN is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels.


Houtani, T., et al. Biochem. Biophys. Res. Commun. 335(2):277-285(2005)
Davies, P.A., et al. J. Biol. Chem. 278(2):712-717(2003)

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Cat# AP5090b
(40 western blots)
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