ZACN Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q401N2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45816 Da |
Antigen Region | 331-360 aa |
Gene ID | 353174 |
---|---|
Other Names | Zinc-activated ligand-gated ion channel, Ligand-gated ion channel zinc-activated 1, Ligand-gated ion-channel receptor L2, ZACN, L2, LGICZ, LGICZ1, ZAC |
Target/Specificity | This ZACN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-360 amino acids from the C-terminal region of human ZACN. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ZACN Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ZACN |
---|---|
Synonyms | L2, LGICZ, LGICZ1, ZAC |
Function | Zinc-activated ligand-gated ion channel. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
Tissue Location | Detected in pancreas, brain, liver, placenta, trachea, kidney, spinal cord, stomach and fetal brain. In the adult brain region expression is detected in the hippocampus, striatum, amygdala and thalamus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZACN is a zinc-activated ligand-gated ion channel that defines a new subgroup of the cysteine-loop superfamily of ligand-gated ion channels.
References
Houtani, T., et al. Biochem. Biophys. Res. Commun. 335(2):277-285(2005)
Davies, P.A., et al. J. Biol. Chem. 278(2):712-717(2003)
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