A4GNT Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q9UNA3 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 39 KDa |
Antigen Region | 11 - 70 aa |
Gene ID | 51146 |
---|---|
Other Names | Alpha-1, 4-N-acetylglucosaminyltransferase, Alpha4GnT, 241-, A4GNT |
Target/Specificity | KLH conjugated synthetic peptide derived from human A4GNT |
Dilution | WB~~ 1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | A4GNT |
---|---|
Function | Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans (PubMed:10430883). Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct (PubMed:10430883). May protect against inflammation-associated gastric adenocarcinomas (By similarity). |
Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
Tissue Location | Detected in stomach and pancreas. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Necessary for the synthesis of type III mucin. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O- glycans.
References
Nakayama J.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:8991-8996(1999).
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