|Reactivity||Human, Mouse, Rat|
|Calculated MW||49 KDa|
|Antigen Region||391 - 450 aa|
|Other Names||BAG family molecular chaperone regulator 4, BAG-4, Bcl-2-associated athanogene 4, Silencer of death domains, BAG4, SODD|
|Target/Specificity||KLH conjugated synthetic peptide derived from human BAG4|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling. Negative regulator of PARK2 translocation to damaged mitochondria.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release (By similarity). Prevents constitutive TNFRSF1A signaling.
Takayama S.,et al.J. Biol. Chem. 274:781-786(1999).
Jiang Y.,et al.Science 283:543-546(1999).
Jiang Y.,et al.Science 283:1852-1852(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 439:331-335(2006).
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