|Reactivity||Human, Mouse, Rat|
|Calculated MW||29 KDa|
|Antigen Region||161 - 220 aa|
|Other Names||Cyclin-G1, Cyclin-G, CCNG1, CCNG, CYCG1|
|Target/Specificity||KLH conjugated synthetic peptide derived from human Cyclin G1|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).|
|Cellular Location||Nucleus. Note=DNA replication foci after DNA damage|
|Tissue Location||High levels in skeletal muscle, ovary, kidney and colon|
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May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
Horne M.C.,et al.J. Biol. Chem. 271:6050-6061(1996).
Bates S.A.,et al.Oncogene 13:1103-1109(1996).
Endo Y.,et al.Genomics 38:92-95(1996).
Reimer C.L.,et al.J. Biol. Chem. 274:11022-11029(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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