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ADIPOR2 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
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| Catalog # | Size | Availability | Price | |
| AP5105c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP5105c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ADIPOR2 Antibody (Center) - Product info | |
| Application | WB, IF, FC
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| Primary Accession | Q86V24 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 43884 Da |
ADIPOR2 Antibody (Center) - Additional info | |
| Gene ID 79602 | |
| Other Names ADIPOR2; PAQR2; Adiponectin receptor protein 2; Progestin and adipoQ receptor family member II | |
| Target/Specificity This ADIPOR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from the Central region of human ADIPOR2. | |
| Dilution WB~~1:100~500WB~~1:1000 IF~~1:10~50 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADIPOR2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADIPOR2 Antibody (Center) - Protein Information | |
| Name ADIPOR2 | |
| Synonyms PAQR2 | |
| Function Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin | |
| Cellular Location Membrane; Multi-pass membrane protein. Note=Localized to the cell membrane and intracellular organelles | |
| Tissue Location Highly expressed in skeletal muscle, liver and placenta. Weakly expressed in brain, heart, colon, spleen, kidney, thymus, small intestine, peripheral blood leukocytes and lung | |
ADIPOR2 Antibody (Center) - Related products
AP5105c: ADIPOR2 Antibody (Center)
ADIPOR2 Antibody (Center) - Application data
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Western blot analysis of ADIPOR2 Antibody (Center) (Cat. #AP5105c) in Hela cell line lysates (35ug/lane).ADIPOR2 (arrow) was detected using the purified Pab.
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Confocal immunofluorescent analysis of ADIPOR2 Antibody (Center) (Cat. #AP5105c) with Hela cell followed by Alexa Fluor搴?489-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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ADIPOR2 Antibody (Center) (Cat. #AP5105c) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ADIPOR2 Antibody (Center) - Research Areas
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BACKGROUND
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.
REFERENCES
Ferguson, J.F., et al. Am. J. Clin. Nutr. 91(3):794-801(2010) Halvatsiotis, I., et al. Cardiovasc Diabetol 9, 10 (2010) Yoshihara, K., et al. J Reprod Med 54 (11-12), 669-674 (2009)
