|Reactivity||Human, Mouse, Rat|
|Calculated MW||83 KDa|
|Antigen Region||381 - 440 aa|
|Other Names||Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2, Cyclic nucleotide-gated channel alpha-2, CNG channel alpha-2, CNG-2, CNG2, CNGA2, CNCA, CNCA1, CNCG2|
|Target/Specificity||KLH conjugated synthetic peptide derived from human CNGA2|
|Format||0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Synonyms||CNCA, CNCA1, CNCG2|
|Function||Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Distler M.,et al.Neuropharmacology 33:1275-1282(1994).
Sjoeblom T.,et al.Science 314:268-274(2006).
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