|Application ||WB, IHC-P, E|
|Other Accession||P27049, Q04211, P78543, Q63073, P62325, P34743, P53348|
|Predicted||Bovine, Chicken, Rat|
|Calculated MW||19209 Da|
|Antigen Region||92-118 aa|
|Other Names||Protein BTG1, B-cell translocation gene 1 protein, BTG1|
|Target/Specificity||This BTG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-118 amino acids from the Central region of human BTG1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BTG1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
BTG1 is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia.
Camina-Tato, M., et al. J. Neuroimmunol. 213 (1-2), 142-147 (2009) Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009) Takahashi, N., et al. Exp. Hematol. 36(12):1760-1770(2008)
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