DGKK Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
---|---|
Primary Accession | Q5KSL6 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 141829 Da |
Antigen Region | 1232-1261 aa |
Gene ID | 139189 |
---|---|
Other Names | Diacylglycerol kinase kappa, DAG kinase kappa, 142 kDa diacylglycerol kinase, Diglyceride kinase kappa, DGK-kappa, DGKK |
Target/Specificity | This DGKK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1232-1261 amino acids from the C-terminal region of human DGKK. |
Dilution | WB~~1:2000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | DGKK Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | DGKK (HGNC:32395) |
---|---|
Function | Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:16210324, PubMed:23949095). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). |
Cellular Location | Cell membrane; Peripheral membrane protein |
Tissue Location | Expressed in testis, and to a lesser extent in placenta. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
DGKK phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).
References
Imai, S., et al. J. Biol. Chem. 280(48):39870-39881(2005)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.