|Application ||WB, IHC-P, E|
|Other Accession||Q61025, Q58CS6|
|Calculated MW||15281 Da|
|Antigen Region||44-71 aa|
|Other Names||Intraflagellar transport protein 20 homolog, hIFT20, IFT20|
|Target/Specificity||This IFT20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-71 amino acids from the Central region of human IFT20.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||IFT20 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Part of intraflagellar transport (IFT) particles involved in ciliary process assembly. May play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium. Also involved in autophagy since it is required for trafficking of ATG16L and the expansion of the autophagic compartment.|
|Cellular Location||Golgi apparatus, cis-Golgi network. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Note=Present at the centrosomes during the cell cycle and associated with the proximal portion of the mother centriole and the lateral aspect of the daughter centriole. Associated with basal body at the base of primary cilia (By similarity).|
|Tissue Location||Expressed in almost all tissues.|
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Provided below are standard protocols that you may find useful for product applications.
IFT20 is part of intraflagellar transport (IFT) particles involved in ciliary process assembly. IFT20 may play a role in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium.
Follit, J.A., et al. Mol. Biol. Cell 17(9):3781-3792(2006)
Jurczyk, A., et al. J. Cell Biol. 166(5):637-643(2004)
Yin, G., et al. Mol. Biol. Rep. 30(4):255-260(2003)
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