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NFYC Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q13952 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 50 KDa |
| Antigen Region | 11 - 70 aa |
| Gene ID | 4802 |
|---|---|
| Other Names | Nuclear transcription factor Y subunit gamma, CAAT box DNA-binding protein subunit C, Nuclear transcription factor Y subunit C, NF-YC, Transactivator HSM-1/2, NFYC |
| Target/Specificity | KLH conjugated synthetic peptide derived from human NFYC |
| Dilution | WB~~ 1:1000 |
| Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | NFYC |
|---|---|
| Function | Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.
References
Nakshatri H.,et al.J. Biol. Chem. 271:28784-28791(1996).
Bellorini M.,et al.Gene 193:119-125(1997).
Dmitrenko V.V.,et al.Gene 197:161-163(1997).
Taira T.,et al.J. Biol. Chem. 274:24270-24279(1999).
Bringuier P.P.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
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