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FKBPL Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9UIM3 |
| Other Accession | Q6MG81, O35450 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 38176 Da |
| Antigen Region | 264-292 aa |
| Gene ID | 63943 |
|---|---|
| Other Names | FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39, FKBPL, DIR1, NG7 |
| Target/Specificity | This FKBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human FKBPL. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FKBPL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FKBPL |
|---|---|
| Synonyms | DIR1, NG7 |
| Function | May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21. |
| Tissue Location | Ubiquitously expressed with higher levels in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
FKBPL has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle.
References
McKeen, H.D., et al. Cancer Res. 70(3):1090-1100(2010)
Sunnotel, O., et al. Reprod. Biol. Endocrinol. 8, 22 (2010)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)
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