|Application ||WB, IHC-P, FC, E|
|Other Accession||Q6MG81, O35450|
|Calculated MW||38176 Da|
|Antigen Region||264-292 aa|
|Other Names||FK506-binding protein-like, WAF-1/CIP1 stabilizing protein 39, WISp39, FKBPL, DIR1, NG7|
|Target/Specificity||This FKBPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-292 amino acids from the C-terminal region of human FKBPL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FKBPL Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in response to X-ray. Regulates p21 protein stability by binding to Hsp90 and p21.|
|Tissue Location||Ubiquitously expressed with higher levels in testis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
FKBPL has similarity to the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The encoded protein is thought to have a potential role in the induced radioresistance. Also it appears to have some involvement in the control of the cell cycle.
McKeen, H.D., et al. Cancer Res. 70(3):1090-1100(2010)
Sunnotel, O., et al. Reprod. Biol. Endocrinol. 8, 22 (2010)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009)
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