Alpha-sarcoglycan Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q16586 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 50 KDa |
Antigen Region | 151 - 210 aa |
Gene ID | 6442 |
---|---|
Other Names | Alpha-sarcoglycan, Alpha-SG, 50 kDa dystrophin-associated glycoprotein, 50DAG, Adhalin, Dystroglycan-2, SGCA, ADL, DAG2 |
Target/Specificity | KLH conjugated synthetic peptide derived from human Alpha-sarcoglycan |
Dilution | WB~~ 1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | SGCA |
---|---|
Synonyms | ADL, DAG2 |
Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
Cellular Location | Cell membrane, sarcolemma; Single- pass type I membrane protein. Cytoplasm, cytoskeleton |
Tissue Location | Most strongly expressed in skeletal muscle. Also expressed in cardiac muscle and, at much lower levels, in lung. In the fetus, most abundant in cardiac muscle and, at lower levels, in lung Also detected in liver and kidney. Not expressed in brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
References
Roberds S.L.,et al.Cell 78:625-633(1994).
McNally E.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:9690-9694(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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