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ENTPD8 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - ENTPD8 Antibody (C-term) AP5161B
    (LEFT)Western blot analysis of ENTPD8 Antibody (C-term) (Cat. #AP5161b) in K562 cell line lysates (35ug/lane).ENTPD8 (arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of ENTPD8 Antibody (C-term) (Cat. #AP5161b) in CHO cell line lysates (35ug/lane).ENTPD8 (arrow) was detected using the purified Pab.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q5MY95
Reactivity Human, Hamster
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 53904 Da
Antigen Region 396-423 aa
Additional Information
Gene ID 377841
Other Names Ectonucleoside triphosphate diphosphohydrolase 8, E-NTPDase 8, NTPDase 8, NTPDase8, ENTPD8
Target/Specificity This ENTPD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the C-terminal region of human ENTPD8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsENTPD8 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ENTPD8
Function Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP.
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations (0)
citation

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Background

ENTPD8 is canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. It is ectonucleoside NTPDases catalyze the hydrolyzis of gamma-and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. ENTPD8 has activity toward ATP, ADP, UTP and UDP, but not toward AMP.

References

Munkonda, M.N., et al. Biochem. Pharmacol. 74(10):1524-1534(2007)
Fausther, M., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (3), G785-G795 (2007)
Knowles, A.F., et al. Biochemistry 45(23):7323-7333(2006)

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$ 365.00
$ 140.00
Cat# AP5161B
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