CD157 Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q10588 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 36 KDa |
Antigen Region | 61 - 120 aa |
Gene ID | 683 |
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Other Names | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, Bone marrow stromal antigen 1, BST-1, Cyclic ADP-ribose hydrolase 2, cADPr hydrolase 2, CD157, BST1 |
Target/Specificity | KLH conjugated synthetic peptide derived from human CD157 |
Dilution | WB~~ 1:1000 |
Format | 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50% |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | BST1 |
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Function | Catalyzes both the synthesis of cyclic ADP-beta-D-ribose (cADPR) from NAD(+), and its hydrolysis to ADP-D-ribose (ADPR) (PubMed:7805847). Cyclic ADPR is known to serve as an endogenous second messenger that elicits calcium release from intracellular stores, and thus regulates the mobilization of intracellular calcium (Probable). May be involved in pre-B-cell growth (Probable). |
Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor |
Tissue Location | Expressed in various tissues including placenta, lung, liver and kidney. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Synthesizes cyclic ADP-ribose, a second messenger that elicits calcium release from intracellular stores. May be involved in pre-B-cell growth.
References
Kaisho T.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:5325-5329(1994).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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