|Application ||WB, IHC-P, FC, E|
|Other Accession||Q6ZPT1, Q2T9Z7|
|Calculated MW||69429 Da|
|Antigen Region||299-326 aa|
|Other Names||Kelch-like protein 9, KLHL9, KIAA1354|
|Target/Specificity||This KLHL9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-326 amino acids from the Central region of human KLHL9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLHL9 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
KLHL9 is substrate-specific adapter for a CUL3-based E3 ubiquitin-protein ligase complex. Within this complex, it controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis.
If you have any additional inquiries please email technical services at email@example.com.