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MPZ Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MPZ Antibody AP51794
    All lanes : Anti-MPZ Antibody at 1:1000 dilution Lane 1: Hela whole cell lysates Lane 2: HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P25189
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 28 KDa
Antigen Region 61 - 120 aa
Additional Information
Gene ID 4359
Other Names Myelin protein P0, Myelin peripheral protein, MPP, Myelin protein zero, MPZ
Target/Specificity KLH conjugated synthetic peptide derived from human MPZ
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.09% (W/V) Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MPZ
Function Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Found only in peripheral nervous system Schwann cells
Research Areas
Citations (0)
citation

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Background

Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.

References

Hayasaka K.,et al.Biochem. Biophys. Res. Commun. 180:515-518(1991).
Hayasaka K.,et al.Biochem. Biophys. Res. Commun. 194:1317-1322(1993).
Pham-Dinh D.,et al.Hum. Mol. Genet. 2:2051-2054(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 350.00
Cat# AP51794
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