ASB15 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8WXK1 |
Other Accession | Q8VHS6, Q8HXA6 |
Reactivity | Human, Mouse |
Predicted | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 65799 Da |
Antigen Region | 258-287 aa |
Gene ID | 142685 |
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Other Names | Ankyrin repeat and SOCS box protein 15, ASB-15, ASB15 |
Target/Specificity | This ASB15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the Central region of human ASB15. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ASB15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ASB15 |
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Function | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ASB15 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
References
Szafranski, K., et al. Genome Biol. 8 (8), R154 (2007)
Kohroki, J., et al. FEBS Lett. 579(30):6796-6802(2005)
Yoshida, K. Int. J. Mol. Med. 16(2):343-347(2005)
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