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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NCKX2 Antibody   

NCKX2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NCKX2 Antibody AP51866
    Anti-NCKX2 Antibodyat 1:1000 dilution + MCF-7 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 74 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9UI40
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 74 KDa
Additional Information
Gene ID 25769
Other Names Sodium/potassium/calcium exchanger 2, Na(+)/K(+)/Ca(2+)-exchange protein 2, Retinal cone Na-Ca+K exchanger, Solute carrier family 24 member 2, SLC24A2, NCKX2
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name SLC24A2
Synonyms NCKX2
Function Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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Background

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+).

References

Prinsen C.F.M.,et al.J. Neurosci. 20:1424-1434(2000).
Humphray S.J.,et al.Nature 429:369-374(2004).
Kinjo T.G.,et al.Biochemistry 42:2485-2491(2003).

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$ 295.00
Cat# AP51866
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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