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FHL2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FHL2 Antibody AP52007
    All lanes : Anti-FHL2 Antibody at 1:1000 dilution Lane 1: HepG2 whole cell lysates Lane 2: HT-1080 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 32 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q14192
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 32 KDa
Additional Information
Gene ID 2274
Other Names Four and a half LIM domains protein 2, FHL-2, LIM domain protein DRAL, Skeletal muscle LIM-protein 3, SLIM-3, FHL2, DRAL, SLIM3
Dilution WB~~ 1:1000
Format 0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name FHL2
Synonyms DRAL, SLIM3
Function May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Expressed in skeletal muscle and heart.
Citations (0)

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Background

May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.

References

Genini M.,et al.DNA Cell Biol. 16:433-442(1997).
Chan K.K.,et al.Gene 210:345-350(1998).
Tanahashi H.,et al.Hum. Mol. Genet. 9:2281-2289(2000).
Qian Z.,et al.Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
Morgan M.J.,et al.Biochem. Biophys. Res. Commun. 225:632-638(1996).

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$ 295.00
Cat# AP52007
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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