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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-Caspase 12 Polyclonal Antibody   

Rabbit Anti-Caspase 12 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - Rabbit Anti-Caspase 12 Polyclonal Antibody AP52032
    Formalin-fixed and paraffin embedded rat testis tissue (high fat) labeled with Anti-NPY/Neuropeptide Y Polyclonal Antibody, Unconjugated (AP52032) at 1:200 followed by conjugation to the secondary antibody and DAB staining
  • IHC-P - Rabbit Anti-Caspase 12 Polyclonal Antibody AP52032
    Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-Caspase 12 Polyclonal Antibody, Unconjugated (AP52032) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O08736
Reactivity Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 47854 Da
Additional Information
Gene ID 12364
Other Names Caspase-12; CASP-12; Casp12
Dilution IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name Casp12
Function Involved in the activation cascade of caspases responsible for apoptosis execution.
Tissue Location Mainly expressed in skeletal muscle and lung.
Citations (0)

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Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Feb 2011].

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$ 295.00
Cat# AP52032
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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