Rabbit Anti-GLP-1R Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IF |
---|---|
Primary Accession | O35659 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 53028 Da |
Gene ID | 14652 |
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Other Names | GLP-1R; GLP1Rc; Glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; Glp1r |
Dilution | WB~~1:100~1:500 IHC-P~~1:100~1:500 FC~~1:20~1:100 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | Glp1r |
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Function | G-protein coupled receptor for glucagon-like peptide 1 (GLP- 1) (PubMed:9568699). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (By similarity). Plays a role in regulating insulin secretion in response to GLP-1 (PubMed:9568699). |
Cellular Location | Cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P43220} |
Tissue Location | Detected in pancreatic islets (at protein level). Detected in pancreatic islets and lungs. |
Provided below are standard protocols that you may find useful for product applications.
Background
This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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