|Application ||WB, IHC-P, IF, FC|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||33068 Da|
|Other Names||TF; TFA; CD142; Tissue factor; Coagulation factor III; Thromboplastin; F3|
|Format||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce|
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.|
|Function||Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.|
|Cellular Location||Isoform 1: Membrane; Single-pass type I membrane protein|
|Tissue Location||Lung, placenta and pancreas.|
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Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited protolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
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