|Application ||WB, IF, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||178188 Da|
|Other Names||KS; KNO; KNO1; Collagen alpha-1(XVIII) chain; COL18A1|
|Format||0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce|
|Storage||Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.|
|Function||COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.|
|Cellular Location||Secreted, extracellular space, extracellular matrix|
|Tissue Location||Present in multiple organs with highest levels in liver, lung and kidney|
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COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
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