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FYTD1 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FYTD1 Antibody  (N-term) AP5223a
    (LEFT)Western blot analysis of FYTD1 Antibody (N-term) (Cat. #AP5223a) in A375 cell line lysates (35ug/lane).FYTD1 (arrow) was detected using the purified Pab.(RIGHT)Western blot analysis of FYTD1 Antibody (N-term) (Cat. #AP5223a) in mouse liver tissue lysates (35ug/lane).FYTD1 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - FYTD1 Antibody  (N-term) AP5223a
    FYTD1 Antibody (N-term) (Cat. #AP5223a) IHC analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FYTD1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q96QD9
Other Accession Q91Z49, Q17QU6
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 35818 Da
Antigen Region 26-54 aa
Additional Information
Gene ID 84248
Other Names UAP56-interacting factor, Forty-two-three domain-containing protein 1, Protein 40-2-3, FYTTD1, UIF
Target/Specificity This FYTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human FYTD1.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFYTD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FYTTD1
Synonyms UIF
Function Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4.
Cellular Location Nucleus, nucleoplasm. Nucleus speckle
Tissue Location Expressed in a wide variety of cancer types.
Research Areas
Citations (0)
citation

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Background

FYTD1 required for mRNA export from the nucleus to the cytoplasm. This protein acts as an adapter that uses the BAT1/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. FYTD1 associates with spliced and unspliced mRNAs simultaneously with THOC4.

References

Hautbergue, G.M., et al. Curr. Biol. 19(22):1918-1924(2009)
Pope, S.N., et al. J. Steroid Biochem. Mol. Biol. 94 (1-3), 203-208 (2005)

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$ 365.00
$ 140.00
Cat# AP5223a
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