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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-BAMBI Polyclonal Antibody   

Rabbit Anti-BAMBI Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Rabbit Anti-BAMBI Polyclonal Antibody AP52256
    L1 rat brain lysates L2 rat kidney lysates probed with Anti BAMBI Polyclonal Antibody, Unconjugated (AP52256) at 1:200 overnight at 4˚C. Followed by conjugation to secondary antibody at 1:3000 for 90 min at 37˚C. Predicted band 29kD. Observed band size:29kD.
  • FC - Rabbit Anti-BAMBI Polyclonal Antibody AP52256
    Mouse splenocytes probed with Rabbit Anti-BAMBI Polyclonal Antibody, Unconjugated (AP52256) (green) at 1:100 for 40 minutes followed by a FITC conjugated secondary compared to control cells (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13145
Reactivity Human, Mouse, Rat, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 29108 Da
Additional Information
Gene ID 25805
Other Names NMA; BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein NMA; BAMBI
Dilution WB~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Synonyms NMA
Function Negatively regulates TGF-beta signaling.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location High expression in kidney medulla, placenta and spleen; low in kidney cortex, liver, prostate and gut. Not expressed in normal skin, expression is high in melanocytes and in 3 out of 11 melanoma metastases tested
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BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.

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$ 295.00
Cat# AP52256
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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