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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-EMR1 Polyclonal Antibody   

Rabbit Anti-EMR1 Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - Rabbit Anti-EMR1 Polyclonal Antibody AP52265
    Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti-EMR1 Polyclonal Antibody, Unconjugated (AP52265) at 1:200 followed by conjugation to the secondary antibody and DAB staining
  • IHC-P - Rabbit Anti-EMR1 Polyclonal Antibody AP52265
    Formalin-fixed and paraffin embedded human breast carcinoma labeled with Rabbit Anti EMR1 Polyclonal Antibody, Unconjugated (AP52265) at 1:200 followed by conjugation to the secondary antibody and DAB staining
  • FC - Rabbit Anti-EMR1 Polyclonal Antibody AP52265
    Mouse splenocytes probed with Rabbit Anti-EMR1 Polyclonal Antibody, Unconjugated (AP52265) at 1:100 for 30 minutes followed by incubation with a conjugated secondary (green) for 30 minutes compared to control cells (blue), secondary only (light blue) and isotype control (orange).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q14246
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 97683 Da
Additional Information
Gene ID 2015
Other Names TM7LN3; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-like module receptor 1; EMR1 hormone receptor; EMR1
Dilution IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name EMR1
Synonyms TM7LN3
Function Could be involved in cell-cell interactions.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Wide expression; increased levels in peripheral blood mononuclear cells
Citations (0)

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The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in M), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.

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$ 295.00
Cat# AP52265
(40 western blots)
Availability: 5-7 days
Bulk Size
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