RABBIT ANTI-PUMA POLYCLONAL ANTIBODY
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF, IHC-P |
---|---|
Primary Accession | Q96PG8 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 26498 Da |
Gene ID | 27113 |
---|---|
Other Names | JFY1; PUMA; JFY-1; Bcl-2-binding component 3; p53 up-regulated modulator of apoptosis; BBC3 |
Dilution | WB~~1:100~1:500 IHC-P~~1:100~1:500 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | BBC3 |
---|---|
Synonyms | PUMA |
Function | [Isoform 3]: Does not affect cell growth. |
Cellular Location | Note=Contrary to isoforms 1 and 2, isoform 3 does not localize to the mitochondria |
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Provided below are standard protocols that you may find useful for product applications.
Background
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Isoform 3 fails to show any growth-inhibitory or apoptotic activity.
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