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>   home   >   Products   >   Primary Antibodies   >   Rabbit Anti-Tp73 protein Polyclonal Antibody   

Rabbit Anti-Tp73 protein Polyclonal Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Rabbit Anti-Tp73 protein Polyclonal Antibody AP52324
    Mouse Kidney lysates probed with Rabbit Anti-Tp73 Polyclonal Antibody, Unconjugated (AP52324) at 1:300 overnight at 4˚C. Incubate with HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000 for 90min at 37˚C.
  • IHC-P - Rabbit Anti-Tp73 protein Polyclonal Antibody AP52324
    Formalin-fixed and paraffin embedded mouse brain labeled with Rabbit Anti-P73 protein Polyclonal Antibody, Unconjugated (AP52324) at 1:200 followed by conjugation to the secondary antibody and DAB staining
  • IHC-P - Rabbit Anti-Tp73 protein Polyclonal Antibody AP52324
    Formalin-fixed and paraffin embedded human endometrium tissue labeled with Anti-P73 Polyclonal Antibody, Unconjugated AP52324 followed by conjugation to the secondary antibody and DAB staining
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9JJP2
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 69096 Da
Additional Information
Gene ID 22062
Other Names p73; Tp73; TAp73; Tumor protein p73; p53-like transcription factor; p53-related protein; Trp73
Dilution WB~~1:100~1:500
IHC-P~~1:100~1:500
Format0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
StorageStore at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃.
Protein Information
Name Tp73
Function Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Cellular Location Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage.
Tissue Location Found in striatal neurons of mutant huntingtin (htt) transgenic mice (at protein level). Isoform 1 is expressed in the nasal epithelium, the vomeronasal organ, the hippocampus and the hypothalamus.
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Background

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

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$ 295.00
Cat# AP52324
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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