|Application ||WB, FC, E|
|Other Accession||P10629, P49925|
|Calculated MW||26915 Da|
|Antigen Region||200-227 aa|
|Other Names||Homeobox protein Hox-C6, Homeobox protein CP25, Homeobox protein HHOC8, Homeobox protein Hox-3C, HOXC6, HOX3C|
|Target/Specificity||This HOXC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the C-terminal region of human HOXC6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HOXC6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.|
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Provided below are standard protocols that you may find useful for product applications.
This protein belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon.
Zhang, X., et al. J. Cell. Mol. Med. 11(2):299-306(2007)
Hori, Y., et al. PLoS Med. 2 (4), E103 (2005)
Ramachandran, S., et al. Oncogene 24(1):188-198(2005)
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