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HOXC6 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - HOXC6 Antibody (C-term) AP5232b
    HOXC6 Antibody (C-term) (Cat. #AP5232b) western blot analysis in PC-3 cell line lysates (35ug/lane).This demonstrates the HOXC6 antibody detected the HOXC6 protein (arrow).
    detail
  • FC - HOXC6 Antibody (C-term) AP5232b
    HOXC6 Antibody (C-term) (Cat. #AP5232b) flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession P09630
Other Accession P10629, P49925
Reactivity Human
Predicted Mouse, Sheep
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 26915 Da
Antigen Region 200-227 aa
Additional Information
Gene ID 3223
Other Names Homeobox protein Hox-C6, Homeobox protein CP25, Homeobox protein HHOC8, Homeobox protein Hox-3C, HOXC6, HOX3C
Target/Specificity This HOXC6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-227 amino acids from the C-terminal region of human HOXC6.
Dilution WB~~1:1000
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHOXC6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HOXC6
Synonyms HOX3C
Function Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

This protein belongs to the homeobox family, members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC6, is one of several HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon.

References

Zhang, X., et al. J. Cell. Mol. Med. 11(2):299-306(2007)
Hori, Y., et al. PLoS Med. 2 (4), E103 (2005)
Ramachandran, S., et al. Oncogene 24(1):188-198(2005)

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$ 365.00
$ 140.00
Cat# AP5232b
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