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K0415 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, E |
|---|---|
| Primary Accession | O43299 |
| Other Accession | Q3U829 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 88605 Da |
| Antigen Region | 294-322 aa |
| Gene ID | 9907 |
|---|---|
| Other Names | AP-5 complex subunit zeta-1, Adaptor-related protein complex 5 zeta subunit, Zeta5, AP5Z1, KIAA0415, SPG48 |
| Target/Specificity | This K0415 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 294-322 amino acids from the Central region of human K0415. |
| Dilution | IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | K0415 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | AP5Z1 |
|---|---|
| Synonyms | KIAA0415, SPG48 |
| Function | As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair. |
| Cellular Location | Cytoplasm. Nucleus. Note=By SDS-PAGE, 2 isoforms have been observed, the shorter seems to be predominantly nuclear and the longer is mostly cytoplasmic. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein has not been specifically defined.
References
Hillier, L.W., et al. Nature 424(6945):157-164(2003)
Scherer, S.W., et al. Science 300(5620):767-772(2003)
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