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NMDAR1 (Phospho-Ser890) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • IF - NMDAR1 (Phospho-Ser890) Antibody AP52402
    Immunofluorescence analysis of A549 cells, using NMDAR1 (Phospho-Ser890) antibody.
  • IHC - NMDAR1 (Phospho-Ser890) Antibody AP52402
    Immunohistochemistry analysis of paraffin-embedded human brain tissue using NMDAR1 (Phospho-Ser890) antibody.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, IHC
Primary Accession Q05586
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 105373 Da
Additional Information
Gene ID 2902
Other Names Glutamate receptor ionotropic, NMDA 1, GluN1, Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1, NMD-R1, GRIN1, NMDAR1
Dilution IF~~1:100
IHC~~1:50~100
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name GRIN1
Synonyms NMDAR1
Function NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density Note=Enriched in postsynaptic plasma membrane and postsynaptic densities.
Research Areas
Citations (0)

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Background

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity).

References

Foldes R.L.,et al.Gene 131:293-298(1993).
Karp S.J.,et al.J. Biol. Chem. 268:3728-3733(1993).
Planells-Cases R.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:5057-5061(1993).
Zimmer M.,et al.Gene 159:219-223(1995).
Nash N.R.,et al.J. Neurochem. 69:485-493(1997).

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$ 295.00
Cat# AP52402
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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