|Reactivity||Human, Mouse, Rat|
|Calculated MW||98314 Da|
|Other Names||Proto-oncogene vav, VAV1, VAV|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.|
|Tissue Location||Widely expressed in hematopoietic cells but not in other cell types|
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Provided below are standard protocols that you may find useful for product applications.
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Coppola J.,et al.Cell Growth Differ. 2:95-105(1991).
Denkinger D.J.,et al.Biochim. Biophys. Acta 1491:253-262(2000).
Grimwood J.,et al.Nature 428:529-535(2004).
Katzav S.,et al.Mol. Cell. Biol. 11:1912-1920(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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