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Androgen Receptor (Phospho-Tyr363) Antibody

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Androgen Receptor (Phospho-Tyr363) Antibody AP52536
    Western blot analysis of extracts from Jurkat cells, treated with UV (15mins), using Androgen Receptor (Phospho-Tyr363) antibody.
  • WB - Androgen Receptor (Phospho-Tyr363) Antibody AP52536
    Western blot analysis of extracts from HuvEc cells (Lane 2), COS7 cells (Lane 3) and JK cells (Lane 4), using Androgen Receptor (Phospho-Tyr363) Antibody. The lane on the left is treated with synthesized peptide.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P10275
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 98989 Da
Additional Information
Gene ID 367
Other Names Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4, AR, DHTR, NR3C4
Dilution WB~~1:1000
Format Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions-20℃
Protein Information
Name AR
Synonyms DHTR, NR3C4
Function Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.
Cellular Location Nucleus. Cytoplasm. Note=Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of GNB2L1
Tissue Location Isoform 2 is mainly expressed in heart and skeletal muscle.
Research Areas
Citations (0)

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Background

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

References

Lubahn D.B.,et al.Mol. Endocrinol. 2:1265-1275(1988).
Chang C.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:7211-7215(1988).
Tilley W.D.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:327-331(1989).
Lubahn D.B.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:9534-9538(1989).
Govindan M.V.,et al.Mol. Endocrinol. 4:417-427(1990).

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$ 295.00
Cat# AP52536
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
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