|Reactivity||Human, Mouse, Rat|
|Calculated MW||64505 Da|
|Other Names||Paxillin, PXN|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).|
|Cellular Location||Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Note=Colocalizes with integrins at the cell periphery.|
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Provided below are standard protocols that you may find useful for product applications.
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
Salgia R.,et al.J. Biol. Chem. 270:5039-5047(1995).
Yamagata K.,et al.Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases.
Mazaki Y.,et al.J. Biol. Chem. 272:7437-7444(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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