|Application ||WB, IHC|
|Calculated MW||85838 Da|
|Other Names||ATR-interacting protein, ATM and Rad3-related-interacting protein, ATRIP, AGS1|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.|
|Cellular Location||Nucleus. Note=Redistributes to discrete nuclear foci upon DNA damage|
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Provided below are standard protocols that you may find useful for product applications.
Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein.
Cortez D.,et al.Science 294:1713-1716(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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