|Application ||WB, IHC|
|Calculated MW||89406 Da|
|Other Names||Nucleolar transcription factor 1, Autoantigen NOR-90, Upstream-binding factor 1, UBF-1, UBTF, UBF, UBF1|
|Format||Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.|
|Function||Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.|
|Cellular Location||Nucleus, nucleolus.|
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Provided below are standard protocols that you may find useful for product applications.
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
Jantzen H.M.,et al.Nature 344:830-836(1990).
Chan E.K.L.,et al.J. Exp. Med. 174:1239-1244(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kwon H.,et al.J. Biol. Chem. 269:30140-30146(1994).
Beckmann H.,et al.Science 270:1506-1509(1995).
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