|Application ||WB, IHC-P, FC, E|
|Other Accession||Q6AY84, Q9CZC8, P83939|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||46382 Da|
|Antigen Region||10-37 aa|
|Other Names||Secernin-1, SCRN1, KIAA0193|
|Target/Specificity||This SCRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human SCRN1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SCRN1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates exocytosis in mast cells. Increases both the extent of secretion and the sensitivity of mast cells to stimulation with calcium (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described.
Suda, T., et al. Cancer Sci. 97(5):411-419(2006)
Way, G., et al. Mol. Biol. Cell 13(9):3344-3354(2002)
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