|Application ||WB, ICC|
|Calculated MW||96 KDa|
|Other Names||Antigen identified by monoclonal;BB2;BB 2;BB2;CD 54;CD_antigen=CD54;CD54;CD54 antigen; Cell surface glycoprotein P3.58;Human rhinovirus receptor;ICAM 1;ICAM-1;ICAM1; ICAM1_HUMAN;Intercellular adhesion molecule 1;intercellular adhesion molecule 1 (CD54), human rhinovirus receptor;Major group rhinovirus receptor;MALA 2;MALA2;MyD 10;MyD10; P3.58;Surface antigen of activated B cells;Surface antigen of activated B cells, BB2.|
|Format||Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Simmons D.,et al.Nature 331:624-627(1988).
Staunton D.E.,et al.Cell 52:925-933(1988).
Tomassini J.E.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:4907-4911(1989).
Voraberger G.F.,et al.J. Immunol. 147:2777-2786(1991).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.