SMAGP Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q0VAQ4 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 10679 Da |
Antigen Region | 46-75 aa |
Gene ID | 57228 |
---|---|
Other Names | Small cell adhesion glycoprotein, Small transmembrane and glycosylated protein, SMAGP |
Target/Specificity | This SMAGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human SMAGP. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SMAGP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SMAGP |
---|---|
Function | May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation. |
Cellular Location | Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle membrane; Single-pass type III membrane protein. Note=Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913) Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429). |
Tissue Location | Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
SMAGP may play a role in epithelial cell-cell contacts. SMAGP may play a role in tumor invasiveness and metastasis formation.
References
Tarbe, N.G., et al. Int. J. Cancer 117(6):913-922(2005)
Tarbe, N.G., et al. Oncogene 23(19):3395-3403(2004)
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