|Application ||WB, IHC-P, FC, E|
|Calculated MW||10679 Da|
|Antigen Region||46-75 aa|
|Other Names||Small cell adhesion glycoprotein, Small transmembrane and glycosylated protein, SMAGP|
|Target/Specificity||This SMAGP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the Central region of human SMAGP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SMAGP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation.|
|Cellular Location||Cell membrane; Single-pass type III membrane protein. Cytoplasmic vesicle membrane; Single-pass type III membrane protein. Note=Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions (PubMed:15021913). Detected on cytoplasmic membranes in undifferentiated tumors (PubMed:15986429)|
|Tissue Location||Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
SMAGP may play a role in epithelial cell-cell contacts. SMAGP may play a role in tumor invasiveness and metastasis formation.
Tarbe, N.G., et al. Int. J. Cancer 117(6):913-922(2005)
Tarbe, N.G., et al. Oncogene 23(19):3395-3403(2004)
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