|Application ||WB, IP|
|Calculated MW||98 KDa|
|Other Names||96 kDa nucleoporin;98 kDa nucleoporin;ADAR2;ADIR2;GLFG-repeat containing nucleoporin; Nuclear pore complex protein Nup96;Nuclear pore complex protein Nup98 Nup96;Nucleoporin 98kD;nucleoporin 98kDa;Nucleoporin Nup96;Nucleoporin Nup98;NUP196;NUP96;Nup98;Nup98-Nup96;NUP98_HUMAN.|
|Format||Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50% glycerol|
|Storage||Store at -20 °C.Stable for 12 months from date of receipt|
|Function||Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup98 and Nup96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC.|
|Cellular Location||Nucleus. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Nucleus, nuclear pore complex. Note=Nup96 is localized to the nucleoplasmic side of the nuclear pore complex (NPC), at or near the nucleoplasmic basket Dissociates from the dissasembled NPC structure early during prophase of mitosis. Colocalized with NUP153 and TPR to the nuclear basket of NPC. Detected in diffuse and discrete intranuclear foci. Remained localized to the nuclear membrane after poliovirus (PV) infection|
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Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Nup98 and Nup96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC.
Borrow J.,et al.Nat. Genet. 12:159-167(1996).
Arai Y.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Fontoura B.M.A.,et al.J. Cell Biol. 144:1097-1112(1999).
Borrow J.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
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