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LRRFIP1 Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • WB - LRRFIP1 Antibody AP52750
    Western blot detection of LRRFIP1 in Raji,C2C12,MCF7 and Jurkat cell lysates using LRRFIP1 mouse mAb (1:1000 diluted).Predicted band size:89KDa.Observed band size:160KDa.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q32MZ4
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 160 KDa
Additional Information
Gene ID 9208
Other Names FLAP1;FLIIAP 1;GC binding factor 2;GCF2;HUFI1;Leucine rich repeat (in FLII) interacting protein 1;Leucine rich repeat flightless interacting protein 1;LRR FLII interacting protein 1;LRRFIP 1;Lrrfip1;MGC10947;MGC119738;MGC119739;NEDD8 conjugating enzyme;TAR RNA interacting protein;TAR RNA-interacting protein;Transcription factor 9 like;TRIP.
Dilution WB~~1:1000
Format Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.02% sodium azide, 50%,glycerol
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name LRRFIP1
Synonyms GCF2, TRIP
Function Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Ubiquitously expressed.
Citations (0)

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Background

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

References

Reed A.L.,et al.J. Biol. Chem. 273:21594-21602(1998).
Wilson S.A.,et al.Nucleic Acids Res. 26:3460-3467(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Fong K.S.K.,et al.Genomics 58:146-157(1999).
Khachigian L.M.,et al.Circ. Res. 84:1258-1267(1999).

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$ 295.00
Cat# AP52750
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
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