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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Hsp90 beta Antibody   

Hsp90 beta Antibody

Purified Mouse Monoclonal Antibody (Mab)

     
  • WB - Hsp90 beta Antibody AP52821
    Western blot detection of Hsp90 beta in Hela,3T3,C6,CHO-K1 and COS7 cell lysates using Hsp90 beta mouse mAb (1:2000 diluted).Exposion time: 4min.Predicted band size:90KDa.Observed band size:90KDa.
  • ICC - Hsp90 beta Antibody AP52821
    Immunocytochemistry staining of HeLa cells fixed with 4% Paraformaldehyde and using anti-Hsp90 beta mouse mAb (dilution 1:200).
  • IP - Hsp90 beta Antibody AP52821
    Immunoprecipitation analysis of Hela cell lysates using Hsp90 beta mouse mAb.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, ICC, IP
Primary Accession P08238
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype IgG1
Calculated MW 90 KDa
Additional Information
Gene ID 3326
Other Names HSP90AB1;90 kda heat shock protein beta HSP90 beta;D6S182;FLJ26984;Heat shock 84 kDa;Heat shock 90kD protein 1, beta;Heat shock 90kDa protein 1 beta;Heat shock protein 90kDa alpha (cytosolic) class B member 1;Heat shock protein beta;Heat shock protein HSP 90 beta;Heat shock protein HSP 90-beta;HS90B_HUMAN;HSP 84;HSP 90;HSP 90 b;HSP 90b;HSP84;HSP90 BETA;hsp90ab1;HSP90B;HSPC2;HSPCB.
Dilution WB~~1:2000
ICC~~1:200
IP~~1:500
Format Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage Store at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name HSP90AB1
Synonyms HSP90B, HSPC2, HSPCB
Function Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Cellular Location Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)

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Background

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.

References

Rebbe N.F.,et al.Gene 53:235-245(1987).
Rebbe N.F.,et al.J. Biol. Chem. 264:15006-15011(1989).
Hoffmann T.,et al.Gene 74:491-501(1988).
Lu L.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Wiemann S.,et al.Genome Res. 11:422-435(2001).

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$ 295.00
Cat# AP52821
Size:
Quantity:
(40 western blots)
Availability: 5-7 days
Bulk Size
Seasonal Special on Bulk Order
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